Hematology Case 58
Hematology Case 58
Female patient 30 years old
No complain - Routine check up and screening.
CBC:
- WBC: 10.7x103 /uL.
- HGB: 12.1 g/dL - MCV: 100.2 fL -MCH: 30 pG - MCHC: 30 % - RDW: 16.4 %
- Platelet: 313 x103 /uL
HGB electrophoresis : See below
HGB separation by HPLC revealed:
HGB F: 2.8%
P3 : 43.8% **
HGB A: 44.3
HGB A2: 2.2
HGB S: 2%
Heterozygous for unknown abnormal HGB separated at HGB N-Baltimore zone. Many other abnormal HGBs can be separated at this zone.
Family history and molecular study are recommended.