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25-Howell–Jolly bodies (RBC inclusion)
Image from a case of megaloblastic anemia due to severe vitamin B12 deficiency.Definition: Howell–Jolly bodies are typically round, smooth, and single, and represent nuclear remnants of dense chromatin. They are frequently found in smears of asplenic individuals or in megaloblastic anemia.24- Click here to show comment
24-RBCs morphological abnormalities
1- Dacrocyte2- Stomatocyte3- Polychromatic RBCs4- Ovalocyte23- Click here to show comment
23- Polychromatic RBCs
Polychromatic RBCs represents stained reticulocytes22- Click here to show comment
22- Macrocyte (Macrocytic RBCs)
Photos from a patient of megaloblastic anemia.Normal erythrocytes are approximately the same size as the nuclei of small lymphocytes, about 8 μm in diameter.21- Click here to show comment
21- RBC Basophilic Stippling
Photo 1 is from a patient of megaloblastic anemia.Photos 2,3 and 4 are from a patient of myeloproliferative disorder.20- Click here to show comment
20- Sickle Cell Solubility Test
Tube 1 : NegativeTube 2 : Positive"4 Photos for different cases"18- Click here to show comment
18- Rouleaux formation of RBC
"2 Pics" from a known case of plasma cell myeloma17- Click here to show comment
17- Peripheral blood smear from a patient with sickle cell disease illustrates the spectrum of RBC findings including:
2 pics1. sickle cells
2. Howell-Jolly bodies.
3. Polychromatophilic RBCs
4. Target cell
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16- Degenerative changes in blood cell morphology with samples that are collected in EDTA
4 Pictures show degenerating neutrophil with indistinct nuclear segmentation and many vacuoles and Erythrocytes are crenated.
Morphologyical changes In erythrocytes : erythrocytes began to show poikilocytosis with crenated forms and cytoplasmic spikes (burr cells, echinocytes) Morphological changes in granulocytes : include cytoplasmic rupture, loss of nuclear shape, elongation or indistinct segmentation of granulocyte nuclei, loss of chromatin definition (appear to have liquefied), pyknotic nuclei (necrobiotic forms), degranulation and cytoplasmic vacuolation... Blood film should be made within 5 hours of collection from blood anticoagulant with EDTA to avoid degenerative changes12- Click here to show comment
12-
Golf ball inclusion
Hemoglobin H Disease
BCB-stained PB smear
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10-
1. Macrocyte
2. Giant Platelet
3. Myeloblast
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9- Dimorphic RBC "RBC Double Population"
UP: Microscopic pictures "3" DOWN: RBC Histogram for the same case7- Click here to show comment
7- PB film of a case of Beta-Thalassemia Major showing:
- dimorphic RBCs population (normo- and hypo-chromic)
- nRBCs
- Fragmented RBCs
- Microspherocytes
- Target cells
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6-
1. Echinocytes/Burr RBC
2. Basophilic Stippling
3. Microspherocyte
4. Elliptocyte (cigar-shaped) RBC
5. Polychromatic Ovalocytes
6. Tear-drop RBCs (Dacrocytes)
7. Elliptocyte (cigar-shaped) RBC
8. Ovalocytes
9. Polychromatic Ovalocytes
10. Schistocytes (Fragmented RBCs)