Hematology Case 19
Hematology Case 19
Presented By Dr Azza Abou Alam
Released on 19-10-2019Patient Data
Patient Data
24 year old male
Clinical Data
Clinical Data
A known case of SCD presented with severe anemia and leukocytosis. He suffered from infection and severe bone pain and He received blood transfusion 2 days ago.
Related Laboratory Results
Related Laboratory Results
CBC, Peripheral Blood Smear, Hb electrophoresis by HPLC & capillary electrophoresis - See Below
Case Picture(s) / Photo(s)
Case Picture(s) / Photo(s)
Comment / Findings
Comment / Findings
Know case of SCD His electrophoresis on both HPLC & capillary electrophoresis reveals HbS , HbD, HbA2 , Hb F & HbA.
These findings are consistent with transfused SCD with Sickle cell/Hb D disease double heterozygosity phenotype.
Both HbS and Hb D interact together to produce moderately severe haemolytic anaemia , sickeled cells and target cells are seen
Final Diagnosis
Final Diagnosis
Transfused sickle cell/Hb D disease double heterozygosity