Hematology Case 19
Hematology Case 19
Presented By Dr Azza Abou Alam
Released on 19-10-201924 year old male
A known case of SCD presented with severe anemia and leukocytosis. He suffered from infection and severe bone pain and He received blood transfusion 2 days ago.
CBC, Peripheral Blood Smear, Hb electrophoresis by HPLC & capillary electrophoresis - See Below
Know case of SCD His electrophoresis on both HPLC & capillary electrophoresis reveals HbS , HbD, HbA2 , Hb F & HbA.
These findings are consistent with transfused SCD with Sickle cell/Hb D disease double heterozygosity phenotype.
Both HbS and Hb D interact together to produce moderately severe haemolytic anaemia , sickeled cells and target cells are seen
Transfused sickle cell/Hb D disease double heterozygosity